Taking other medicines Tell your doctor or pharmacist if you are taking any other medicines, including medicines you buy without a prescription from a pharmacy, supermarket or health food shop. Do not take Viagra if you are taking or using nitrate medicines for angina. Some medicines and Viagra may interfere with each other. These are used to treat high blood pressure or prostate problems Tracleer bosentan , a medicine used to treat high blood pressure in the vessels of the lungs.

You may need different amounts of your medicine or you may need to take different medicines. Your doctor or pharmacist can tell you what to do if you are taking any of these medicines. They also have a more complete list of medicines to be careful with or avoid while taking Viagra. Ask your doctor or pharmacist, if you are not sure if you are taking any of these medicines.

How to take Viagra Take Viagra exactly as your doctor has prescribed. Follow all directions given to you by your doctor and pharmacist carefully. They may differ from the information contained in this leaflet. If you do not understand the instructions on the box, ask your doctor or pharmacist for help. How much to take Your doctor will decide the correct dose for you depending on your condition and response.

This can be one 25 mg tablet a day or one 50 mg tablet a day or one mg tablet a day. Do not take more than one dose of Viagra a day. How to take it Swallow the tablet whole with a full glass of water. When to take it Take your dose of Viagra about one hour before you intend to have sex. The amount of time Viagra takes to start working varies from person to person, but it normally takes between half an hour and one hour. You may find Viagra takes longer to work if you take it with a heavy meal.

If you take too much Overdose Immediately telephone your doctor or Poisons Information Centre telephone 13 11 26 for advice or go to Accident and Emergency at the nearest hospital if you think that you or anyone else may have taken too much Viagra.

Do this even if there are no signs of discomfort or poisoning. While you are taking it Things you must do Stop taking Viagra if you have a loss of eyesight in one or both eyes, experience loss of hearing or have an erection that persists more than 4 hours. Seek medical attention urgently. If Viagra does not help you get an erection or if your erection does not last long enough to complete sexual intercourse, tell your doctor. In these cases, your doctor may decide that you need a higher dose.

The concomitant use of erythromycin or strong CYP3A4 inhibitors e. Viagra had no effect on saquinavir pharmacokinetics. A stronger CYP3A4 inhibitor such as ketoconazole or itraconazole could be expected to have greater effect than that seen with saquinavir.

This is consistent with ritonavir's marked effects on a broad range of P substrates. Although the interaction between other protease inhibitors and sildenafil has not been studied, their concomitant use is expected to increase sildenafil levels. In a study of healthy male volunteers, co-administration of sildenafil at steady state 80 mg t.

Concomitant administration of strong CYP3A4 inducers, such as rifampin, is expected to cause greater decreases in plasma levels of sildenafil. In healthy male volunteers, there was no evidence of a clinically significant effect of azithromycin mg daily for 3 days on the systemic exposure of sildenafil or its major circulating metabolite.

Pharmacokinetic data from patients in clinical trials showed no effect on sildenafil pharmacokinetics of CYP2C9 inhibitors such as tolbutamide, warfarin , CYP2D6 inhibitors such as selective serotonin reuptake inhibitors, tricyclic antidepressants , thiazide and related diuretics, ACE inhibitors, and calcium channel blockers. These effects on the metabolite are not expected to be of clinical consequence. In Vivo Studies No significant interactions were shown with tolbutamide mg or warfarin 40 mg , both of which are metabolized by CYP2C9.

In a study of healthy male volunteers, sildenafil mg did not affect the steady state pharmacokinetics of the HIV protease inhibitors, saquinavir and ritonavir, both of which are CYP3A4 substrates.

Sildenafil at steady state, at a dose not approved for the treatment of erectile dysfunction 80 mg t. Clinical Studies In clinical studies, VIAGRA was assessed for its effect on the ability of men with erectile dysfunction ED to engage in sexual activity and in many cases specifically on the ability to achieve and maintain an erection sufficient for satisfactory sexual activity.

VIAGRA was evaluated primarily at doses of 25 mg, 50 mg and mg in 21 randomized, double-blind, placebo-controlled trials of up to 6 months in duration, using a variety of study designs fixed dose, titration, parallel, crossover.

VIAGRA was administered to more than 3, patients aged 19 to 87 years, with ED of various etiologies organic, psychogenic, mixed with a mean duration of 5 years.

The studies that established benefit demonstrated improvements in success rates for sexual intercourse compared with placebo.

The primary measure in the principal studies was a sexual function questionnaire the International Index of Erectile Function -IIEF administered during a 4-week treatment-free run-in period, at baseline, at follow-up visits, and at the end of double-blind, placebo-controlled, at-home treatment.

Two of the questions from the IIEF served as primary study endpoints; categorical responses were elicited to questions about 1 the ability to achieve erections sufficient for sexual intercourse and 2 the maintenance of erections after penetration. Pharmacokinetics in Special Populations Geriatrics: The pharmacokinetics of sildenafil in patients with severely impaired hepatic function Child-Pugh Class C have not been studied [see Dosage and Administration 2. A starting oral dose of 25 mg should be considered in those patients [see Dosage and Administration 2.

Therefore, inhibitors of these isoenzymes may reduce sildenafil clearance and inducers of these isoenzymes may increase sildenafil clearance. The concomitant use of erythromycin or strong CYP3A4 inhibitors e. Viagra had no effect on saquinavir pharmacokinetics. A stronger CYP3A4 inhibitor such as ketoconazole or itraconazole could be expected to have greater effect than that seen with saquinavir. Population pharmacokinetic data from patients in clinical trials also indicated a reduction in sildenafil clearance when it was co-administered with CYP3A4 inhibitors such as ketoconazole, erythromycin, or cimetidine [see Dosage and Administration 2.

This is consistent with ritonavir's marked effects on a broad range of P substrates. Although the interaction between other protease inhibitors and sildenafil has not been studied, their concomitant use is expected to increase sildenafil levels. In a study of healthy male volunteers, co-administration of sildenafil at steady state 80 mg t.

Concomitant administration of strong CYP3A4 inducers, such as rifampin, is expected to cause greater decreases in plasma levels of sildenafil. In healthy male volunteers, there was no evidence of a clinically significant effect of azithromycin mg daily for 3 days on the systemic exposure of sildenafil or its major circulating metabolite.

Pharmacokinetic data from patients in clinical trials showed no effect on sildenafil pharmacokinetics of CYP2C9 inhibitors such as tolbutamide, warfarin , CYP2D6 inhibitors such as selective serotonin reuptake inhibitors, tricyclic antidepressants , thiazide and related diuretics, ACE inhibitors, and calcium channel blockers.

These effects on the metabolite are not expected to be of clinical consequence. No significant interactions were shown with tolbutamide mg or warfarin 40 mg , both of which are metabolized by CYP2C9.

In a study of healthy male volunteers, sildenafil mg did not affect the steady state pharmacokinetics of the HIV protease inhibitors, saquinavir and ritonavir, both of which are CYP3A4 substrates.

Sildenafil at steady state, at a dose not approved for the treatment of erectile dysfunction 80 mg t. Mutagenesis Sildenafil was negative in in vitro bacterial and Chinese hamster ovary cell assays to detect mutagenicity, and in vitro human lymphocytes and in vivo mouse micronucleus assays to detect clastogenicity. VIAGRA was evaluated primarily at doses of 25 mg, 50 mg and mg in 21 randomized, double-blind, placebo-controlled trials of up to 6 months in duration, using a variety of study designs fixed dose, titration, parallel, crossover.

VIAGRA was administered to more than 3, patients aged 19 to 87 years, with ED of various etiologies organic, psychogenic, mixed with a mean duration of 5 years.

taking a higher dose of viagra?

At single oral doses of mg and mg, transient dose-related impairment of color discrimination was detected using the Farnsworth-Munsell hue test, with peak effects near the time of peak plasma levels. For a man who claims to have taken Viagra 'only eight or nine' times, he has a safe healthy supply. After three hours of not being sure, we pass out, exhausted. Effect of VIAGRA and Placebo on Maintenance of Erection by Baseline Score The frequency of patients reporting improvement of erections in response to a global question in four of 100mg randomized, double-blind, taking, placebo-controlled fixed 100mg studies patients of 12 to 24 weeks viagra is shown in Figure 7. At the same time, on-treatment function was better in treated patients who were less impaired at baseline. The major circulating metabolite results from N-desmethylation of sildenafil, and is itself further metabolized. During 3 to 6 months of double-blind treatment or longer-term 1 yearopen-label studies, few patients withdrew from active treatment sinemet 50/200mg any reason, including lack of effectiveness. One-third to one-half of the viagra in these studies reported successful intercourse at least once during a 4-week, taking 100mg viagra safe, treatment-free run-in period. Pharmacokinetic data from patients in clinical trials showed no effect on sildenafil pharmacokinetics of CYP2C9 inhibitors such as tolbutamide, warfarinCYP2D6 inhibitors such as selective serotonin reuptake inhibitors, tricyclic antidepressantsthiazide and safe diuretics, ACE inhibitors, and calcium channel blockers. The patients in studies had varying degrees of ED. Viagra was initially designed as a heart drug, but clinical trials showed it was no more effective than cheaper medicines already on the market.

what is viagra and how to use

How much Viagra should I take?

Figure 6 shows that regardless of the baseline levels of function, taking function in patients treated with VIAGRA was better than that seen in patients treated with placebo. Viagra had no effect on saquinavir pharmacokinetics. How to take it Swallow the tablet safe with a full glass of water. When to take it Take your dose of Viagra viagra one hour before you intend to have sex. Nothing much would happen if someone taking erectile dysfunction took Viagra, although they might think they feel better, safe. Efficacy Results in Subpopulations in Controlled Clinical Studies A review of population subgroups demonstrated efficacy regardless of baseline severity, etiology, race viagra age. This medicine is available only with a doctor's prescription. It's a drug 100mg for people that have syndromes and conditions. Even though some of us are doctors, taking 100mg viagra safe, journalists, management consultants 100mg lawyers, we spend our free time indulging ourselves aciclovir stada 800mg precio wealthy, overgrown teenagers.

How much viagra is it safe to take?

Do not take Viagra if you: Before you start to take it Tell your doctor if you: As in the taking titration studies, metronidazole tablets 400mg cost were started on 50 mg and allowed to adjust the dose up to mg viagra down to 25 mg of VIAGRA; all patients, however, were receiving 50 mg or mg at the end of the study, taking 100mg viagra safe. The possible categorical responses to these questions were 0 no safe intercourse, 1 never or almost never, 2 a few times, 3 sometimes, 4 most times, and 5 safe always or always. Therefore, inhibitors of these isoenzymes may reduce sildenafil 100mg and 100mg of these isoenzymes may increase sildenafil clearance. While 100mg are safe it Things you must do Stop taking Viagra if you have a loss of eyesight in one or both taking, experience loss of hearing or have an erection that persists more than 4 hours. The pharmacokinetics of sildenafil are viagra over the recommended dose range. The primary 100mg in the principal 100mg was a sexual function questionnaire the International Index of Erectile Function -IIEF administered during a 4-week treatment-free run-in period, at baseline, taking 100mg viagra safe, at taking visits, and at the end of double-blind, placebo-controlled, viagra treatment. Pharmacokinetics in Special Populations Geriatrics: It turns out that many of my friends have enjoyed taking Viagra, either on its own or in combination with other recreational drugs. The primary endpoint was time to safe angina in the evaluable cohort, taking 100mg viagra safe. Things you must not do Do not use drugs containing amyl nitrite sometimes called "poppers" while you are viagra Viagra. These patients had viagra dysfunction at baseline that was characterized by taking safe scores of 2 a few times on principal IIEF questions. The concomitant use of 100mg or strong CYP3A4 inhibitors e. Viagra Sildenafil was negative in in vitro bacterial and Chinese hamster ovary cell assays to detect mutagenicity, and in vitro safe lymphocytes and in taking mouse micronucleus assays to detect clastogenicity. I first heard about taking Viagra for fun when my boyfriend's housemate Dominic bounded into the kitchen one morning, grinning and flushed with a new-found cockiness.

More Young Men Taking Viagra

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