The effects, if any, on the pituitary -gonadal axis in premenopausal women are unknown. Patients treated with lovastatin who develop clinical evidence of endocrine dysfunction should be evaluated appropriately.
Caution should also be exercised if an HMG-CoA reductase inhibitor or other agent used to lower cholesterol levels is administered to patients also receiving other drugs e. This dose produced a total plasma drug exposure 3 to 4 times that of humans given the highest recommended dose of lovastatin drug exposure was measured as total HMG-CoA reductase inhibitory activity in extracted plasma.
A statistically significant increase in pulmonary adenomas was seen in female mice at approximately 4 times the human drug exposure. There was an increase in incidence of papilloma in the non-glandular mucosa of the stomach of mice beginning at exposures of 1 to 2 times that of humans given lovastatin immediate-release. The glandular mucosa was not affected. The human stomach contains only glandular mucosa. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.
Lovastatin 40mg is used along with a proper diet to help lower "bad" cholesterol and fats such as LDL, triglycerides and raise "good" cholesterol HDL in the blood. It belongs to a group of drugs known as "statins. Lowering "bad" cholesterol and triglycerides and raising "good" cholesterol decreases the risk of heart disease and helps prevent strokes and heart attacks. Consult your doctor for more details. Take Lovastatin 40mg by mouth as directed by your doctor, usually once daily with your evening meal.
Some patients may be directed to take Lovastatin 40mg twice daily. Dosage of Lovastatin 40mg is based on your medical condition, response to treatment, age, and other medications you may be taking. Be sure to tell your doctor and pharmacist about all the products you use including prescription drugs, nonprescription drugs, and herbal products. Avoid eating grapefruit or drinking grapefruit juice while using Lovastatin 40mg unless your doctor instructs you otherwise.
Grapefruit can increase the amount of Lovastatin 40mg in your bloodstream. Consult your doctor or pharmacist for more details.
If you also take certain other drugs to lower your cholesterol bile acid-binding resins such as cholestyramine or colestipol , take Lovastatin 40mg 40mg at least 1 hour before or at least 4 hours after taking these medications. These products can react with Lovastatin 40mg 40mg, preventing its full absorption. Take Lovastatin 40mg regularly in order to get the most benefit from it. Remember to take it at the same time s each day. It is important to continue taking Lovastatin 40mg even if you feel well.
Most people with high cholesterol or triglycerides do not feel sick. Lovastatin may harm an unborn baby. Therefore, it is important to prevent pregnancy while taking this medication. Consult your doctor for more details and to discuss the use of reliable forms of birth control such as condoms, birth control pills while taking this medication.
If you become pregnant or think you may be pregnant, tell your doctor right away. It is unknown if this medication passes into breast milk. Because of the possible risk to the infant, breast-feeding while using this drug is not recommended. Consult your doctor before breast-feeding. Store at room temperature away from light and moisture.
Storage temperature ranges differ according to different manufacturers, so consult your pharmacist for more information.
Do not store in the bathroom. Keep all medicines away from children and pets. Do not flush medications down the toilet or pour them into a drain unless instructed to do so.
Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product. See also How to Use section. Drug interactions may change how your medications work or increase your risk for serious side effects.
This document does not contain all possible drug interactions. Do not start, stop, or change the dosage of any medicines without your doctor's approval. Some products that may interact with this drug include: Other medications can affect the removal of lovastatin from your body, which may affect how lovastatin works. People who have had a heart attack will probably be prescribed several different kinds of drugs, including a statin, and lifestyle changes will be strongly urged. In studies involving heart patients, atorvastatin has been shown to reduce the risk of second heart attacks and deaths, strokes, and major heart problems.
In addition, atorvastatin may be a better option for people who have had a heart attack and need greater LDL reduction. Strokes Several statins—atorvastatin, pravastatin, simvastatin, and rosuvastatin Crestor —have been proven to prevent strokes. An analysis by the Cochrane Collaboration found that the available evidence indicates overall that statins reduce the risk of fatal and nonfatal strokes by 22 percent.
What about the other statins? Fluvastatin and pitavastatin have not been clearly proven to reduce heart attacks, strokes, or deaths. Crestor has been shown to reduce heart attacks and deaths, but there is no reason to take it instead of generic atorvastatin, which is about half the price, depending on dose. Getting the right dose Warning about high doses There is one other important issue you should know about as you and your doctor choose a statin.
For people who are at high risk of heart attack—for example, if you have diabetes, are a smoker and have elevated LDL levels—studies indicate that the lower your LDL, the lower the risk of heart attack and stroke. Since higher doses and high intensity statins reduce LDL cholesterol more, the hypothesis has been that they are better and should be used more liberally. But higher doses and high-intensity statins come with more side effects. Higher doses of all statins have been linked to muscle aches, soreness, tenderness, or weakness.
Studies indicate that between one in 20 to one in 10 people who take a statin—regardless of dose—experience these symptoms, and up to 10 percent in some studies have not been able to tolerate an 80 mg dose. Higher doses have also been linked to an increased risk of a life-threatening form of muscle breakdown called rhabdomyolysis.
This can lead to permanent kidney damage, coma, and death. So even if you fall into a category that should receive a high-intensity statin, we advise caution and careful monitoring for the occurrence of side effects. What about low-intensity statins? If you are already taking a low-intensity statin, such as simvastatin 10 mg, pravastatin 10 mg or 20 mg, lovastatin 20 mg, fluvastatin 20 mg or 40 mg, or pitavastatin 1 mg, the new guidelines do not mean that you should necessarily switch to a moderate- or high-intensity statin.
This could be a good time to review your risk factors with your doctor to figure out your current risk level and determine whether or not it makes sense to change to a different statin. Effectiveness and risks How effective are statins? Statins reduce the risk of a first heart attack and repeat heart attacks, as well as the risk of death from heart attacks and other forms of heart disease.
But some have been studied more extensively than others in terms of both their effectiveness and their safety. And ongoing research continues to define how the statins work and how they differ. Although all statins reduce LDL cholesterol levels, they have also been evaluated by three other criteria to determine if the drug:
Lowering "bad" cholesterol and triglycerides and raising "good" cholesterol decreases the risk of heart disease and helps prevent strokes and heart attacks. If these rare effects occur, talk to your doctor. Consult your doctor for more details and to discuss the use of reliable forms of birth control such as condoms, birth control pills while taking Lovastatin 40mg. Reduces nonfatal heart attacks Reduces deaths from heart attacks Reduces the chance of death due to other causes, including stroke and other forms of heart disease Reduction of heart attacks Four statins—atorvastatin Lipitor and genericlovastatin Altoprev, Mevacor, and pricepravastatin Pravachol and genericand simvastatin Zocor and generic —have been proven to reduce the risk of heart attack over three to five years of use. We discuss those safety concerns low more detail below. The problems did not appear to be linked to higher doses of statins. Consult your doctor for more details and to discuss the use of reliable forms lovastatin birth control such as condomsbirth control pills while taking this price. Consult your doctor or pharmacist for more details. Ask your doctor or pharmacist for more information. Also, lovastatin low price, do not split the tablets 80mg hydrocodone red capsule they have a score line and low doctor or pharmacist tells you to do so, lovastatin low price. Before having surgery, tell your doctor or dentist about all the products you use including prescription lovastatinlovastatin low price, nonprescription drugs, and herbal products.
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© Copyright 2017 Altoprev (Lovastatin Extended-Release Tablets): Side Effects, Interactions, Warning, Dosage & Uses.