Limit use to four weeks maximum under close medical supervision. It was recommended that zolpidem be used for short periods of time using the lowest effective dose.
Abrupt withdrawal may cause deliriumseizures, or other severe effects, especially if used for prolonged periods and at high dosages. Failing that, an alternative method may be necessary for some patients, such as a switch to a benzodiazepine equivalent dose of a longer-acting benzodiazepine drug, such as diazepam or chlordiazepoxidefollowed by a gradual reduction in dosage of the long-acting benzodiazepine.
Sometimes for difficult-to-treat patients, an inpatient flumazenil rapid zolpidem program can be used to detoxify from a zolpidem drug dependence or addiction. For this reason, alcoholics or recovering alcoholics may be at increased risk of physical dependency on zolpidem.
Also, zolpidem ct 5 mg, alcoholics and recreational drug users may have an increased likelihood of abuse and or becoming psychologically dependent on zolpidem.
Zolpidem has rarely been associated with drug-seeking behavior ,[ citation needed ] the likelihood of which is amplified in patients with a history of recreational use of drugs or alcohol.
Overdose[ edit ] An overdose of zolpidem may cause excessive sedation, pin-point pupils, or depressed respiratory function, which may progress to coma, and possibly death.
Combined with alcohol, opiates, or other CNS depressants, zolpidem ct 5 mg, it may be even more likely to lead to fatal overdoses.
Zolpidem overdosage can be treated with the benzodiazepine receptor antagonist flumazenilzolpidem ct 5 mg, which displaces zolpidem from its binding site on zolpidem benzodiazepine receptor to rapidly reverse the effects of the zolpidem. Analytical techniques, in general, involve gas or liquid chromatography.
This adverse effect is not unique to zolpidem but also occurs with other hypnotic drugs, zolpidem ct 5 mg. Caution should be exercised by motor vehicle drivers.
As a consequence, the FDA recommended the dose for women be reduced and that prescribers should consider lower doses for men.
Zolpidem causes an increased risk of falls and may induce adverse cognitive effects. Compared with the benzodiazepines, the nonbenzodiazepine including zolpidem sedative-hypnotics appeared to offer few, if any, zolpidem ct 5 mg, significant clinical advantages in efficacy or tolerability in elderly persons.
Newer agents with novel mechanisms of action and improved safety profiles, such as the melatonin receptor agonistswere found to hold promise for the management of chronic insomnia in elderly people. Long-term use of sedative-hypnotics for insomnia lacks an evidence base and has traditionally been discouraged for reasons that include concerns about such potential adverse drug effects as cognitive impairment anterograde amnesiadaytime sedation, motor incoordination, and increased risk of motor vehicle zolpidem and falls, zolpidem ct 5 mg.
In addition, the effectiveness and safety of long-term use of these agents remain to be determined, zolpidem ct 5 mg. More research is needed to evaluate the long-term effects of treatment and the most appropriate management zolpidem for elderly persons with chronic insomnia.
The same trend was found for reflux events in patients without GERD. This is assumed to be due to suppression of arousal during the reflux event, zolpidem ct 5 mg, which zolpidem normally result in a swallowing reflex to clear gastric acid from the esophagus. This medication is usually limited to short treatment periods of 1 to 2 weeks or less.
If you have any questions, ask your doctor or pharmacist. Take this medication by mouth on an empty stomach as directed by your doctor, usually once a night.
Since zolpidem works quickly, take it right before you get into bed. Do not take it with or after a meal because it will not work as quickly, zolpidem ct 5 mg.
Do not take a dose of this drug unless you have time for a full night's sleep of at least 7 to 8 hours. If you have to wake up before that, you may have some memory loss and may have trouble safely doing any activity that requires alertness, such as driving or operating machinery. See also Precautions section. Dosage is based on your gender, age, medical condition, other medications you may be taking, and response to treatment.
Do not increase your dose, take it more often, or use it for longer than prescribed. Do not take more than 10 milligrams a day.
Women are usually prescribed zolpidem lower dose because the drug is removed from the body more slowly than in men. Older adults are usually prescribed a lower dose to decrease the risk of side effects, zolpidem ct 5 mg. This medication may cause withdrawal reactions, especially if it has been used regularly for a long time or in high doses.
In such cases, withdrawal symptoms such as nauseavomitingflushing, zolpidem ct 5 mg, stomach crampsnervousness, shakiness may occur if you suddenly stop using this medication.
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