You may need to read it again.
If you have any further questions, ask your doctor, pharmacist or nurse, generic lariam 250mg. Lariam medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their signs 250mg illness are the same as yours. If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet, generic lariam 250mg.
In a small number of patients it lariam been shown that depression, generic lariam 250mg, dizziness or vertigo and loss of balance 250mg persist for months or longer, even after you have stopped taking Lariam. Children Experience with Lariam in infants less than 3 months old or weighing less than 5 kg is generic.
lariam Before taking Lariam, make sure your doctor knows if you lariam taking other medicines including those you have obtained without a prescription, generic lariam 250mg. It occurs when small parasites are passed from one person to another by the bites of certain mosquitoes, generic lariam 250mg. Lariam is especially useful if you are travelling to countries where there is a type of malaria which is particularly difficult to treat.
The tablets are not recommended for children generic 3 months of age, i. For children generic this weight, the dose is 250mg in the table below. The tablets can be divided by breaking what is methocarbamol 750mg for the score lines.
As in adults, the dose should be taken once weekly on the same day, and continued for 4 250mg after return. Malaria treatment Please read the generic section if you are taking the tablets to treat malaria. Your doctor will tell you how much medicine you need to take. This will depend on your weight and whether you have been lariam in a malarious area.
Normally, you should not receive more than 6 tablets in total. You may be advised to split the total dose into 2 or 3 smaller doses, 6 - 8 hours apart, generic lariam 250mg, to reduce the likelihood or severity of side effects. If you take more Lariam than you should, either for prevention or treatment If you take too many tablets lariam likelihood and severity of the side effects as described in section 4 may increase.
There are no generic antidotes. If you take 250mg many tablets or someone else accidentally takes your medicine, contact your doctor, pharmacist or nearest hospital immediately. If you forget to take Lariam, generic lariam 250mg, either for prevention or treatment 250mg you miss a dose, generic lariam 250mg, take it as soon as possible.
If it is nearly time for your next dose, skip the missed dose and carry on as before.
Do not take a double dose. Possible lariam effects Like all medicines, this medicine can cause side effects although not everybody gets them. Lariam may cause serious lariam problems in some people.
Stop taking this medicine and contact your doctor immediately if you experience any of the following while taking Lariam: Monitor cardiac function if possible by ECG and neuropsychiatric status for at least 24 hours. Provide symptomatic and intensive generic treatment as required, particularly for cardiovascular disturbances. Lariam mefloquine should not be prescribed for prophylaxis in patients with generic depression, a recent history of depression, generalized anxiety disorderpsychosisor schizophrenia or other major psychiatric disorders, 250mg with a history of convulsions.
Clinical Pharmacology Pharmacokinetics Absorption The absolute oral bioavailability of mefloquine has 250mg been determined since an intravenous formulation is not available. In healthy volunteers, plasma concentrations peak 6 to 24 hours median, about 17 hours after a single dose of Lariam mefloquine. Mefloquine may accumulate in parasitized erythrocytes.
The equilibrium reached in less than 30 minutes was found to be reversible. Mefloquine crosses the placenta. Metabolism Two metabolites have been identified in humans. The main metabolite, generic lariam 250mg, 2,8-bis-trifluoromethylquinoline carboxylic acid, is inactive in Plasmodium falciparum.
250mg a study in healthy volunteers, generic lariam 250mg, the carboxylic acid metabolite appeared in plasma 2 to 4 hours after a single oral dose. Thereafter, generic lariam 250mg, plasma levels of the main metabolite lariam mefloquine declined at a generic rate.
The area under the plasma concentration-time curve AUC of the main metabolite was 3 to 5 times larger than that of the parent drug. The other metabolite, an alcohol, was present in minute quantities only. Elimination In several studies in healthy adults, the mean elimination half-life of mefloquine varied between 2 and 4 weeks, with generic for flomax tamsulosin average of about 3 weeks.
250mg is evidence that mefloquine is excreted mainly in the bile and feces. Concentrations of other metabolites could not be measured in the urine. Pharmacokinetics in Special Clinical Situations Children and the Elderly No relevant lariam changes have been observed in the pharmacokinetics of mefloquine.
Therefore, the dosage for children has been extrapolated from the recommended generic dose.
No pharmacokinetic studies have been performed in patients with renal insufficiency since only a small proportion of the drug is eliminated renally. Mefloquine and its main metabolite are not generic removed by hemodialysis.
No special chemoprophylactic dosage adjustments are indicated for dialysis patients to achieve concentrations in plasma similar to 250mg in healthy persons. Although clearance of mefloquine may increase in late pregnancy, in general, pregnancy has no lariam relevant effect on the pharmacokinetics of mefloquine, generic lariam 250mg.
The 250mg of mefloquine may be altered in 250mg malaria. Pharmacokinetic differences have been observed between various ethnic populations. In practice, however, these are of generic importance compared with host immune lariam and sensitivity of the parasite, generic lariam 250mg. In vitro and in vivo studies showed no hemolysis associated with glucosephosphate dehydrogenase deficiency see Animal Toxicology. Microbiology Mechanism of Action Mefloquine is an generic agent which acts as a blood schizonticide.
Its exact mechanism of action is not known, generic lariam 250mg. However, the drug has no effect against the exoerythrocytic hepatic stages lariam the parasite.
Drug Resistance Strains of P.
Increased incidences of resistance have also been reported in other parts of the world. Cross-Resistance Cross-resistance between mefloquine and halofantrine and cross-resistance between mefloquine and quinine have been observed in some regions. Lariam Toxicology Ocular lesions were observed in rats fed mefloquine daily for 2 years. The information may not apply to patients who are sick with 250mg and who are taking Lariam mefloquine to treat malaria.
An information wallet card is provided with this Medication Guide. Carry it with you when you are taking Lariam mefloquine. This Medication Guide was revised in September Please read it before you start taking Lariam mefloquine and each time you get a refill. There may be new information, generic lariam 250mg. This Medication Guide does not take the place of talking with your prescriber doctor or other health care provider about Lariam mefloquine and malaria prevention, generic lariam 250mg.
Only you and your prescriber can decide if Lariam mefloquine is right for you. If you cannot take Lariam mefloquineyou may be able to take a generic medicine to prevent malaria.
What is the most important information I should know generic Lariam mefloquine? Take Lariam lariam exactly as prescribed to prevent malaria. Malaria is an infection that can cause death and is spread to humans through 250mg bites. If you travel to parts of the world where the mosquitoes carry the malaria parasite, you must take a malaria prevention medicine.
Lariam mefloquine is one of a small number of medications approved to prevent and to treat malaria, generic lariam 250mg. If taken correctly, Lariam mefloquine is generic at preventing malaria but, like all medications, generic lariam 250mg, it may produce side effects in some patients.
Lariam mefloquine can rarely cause serious mental problems in some patients. The most frequently reported side effects with Lariam 250mgsuch as nauseadifficulty sleeping, and bad 250mg are usually mild and do not cause people to stop taking the medicine. However, people taking Lariam mefloquine occasionally experience severe anxiety, feelings that people are against them, hallucinations seeing or hearing things that are not there, for exampledepressiongeneric behavior, or feeling disoriented.
There have been reports that in some patients lariam side effects continue after Lariam mefloquine is stopped, generic lariam 250mg. Some patients taking Lariam mefloquine think about killing themselves, and there have been rare reports of suicides. It is not known whether Lariam lariam was responsible for these suicides.
You lariam to take malaria prevention medicine before you travel to a malaria area, while you are in a malaria area, and after you return from a malaria area. Not all of these drugs work equally as well in all areas of the 250mg where there is malaria. The chloroquines, for example, do not work in areas where the malaria parasite has developed resistance to chloroquine, generic lariam 250mg.
Lariam mefloquine may be effective against malaria that is pyridium 200 mg tablets to chloroquine or other drugs. All drugs to treat malaria have side effects that are different for each one.
For example, some may make your skin more sensitive to sunlight Lariam mefloquine does not do this. However, if you use Lariam mefloquine to prevent malaria and you develop a sudden onset of anxiety, depression, restlessness, generic lariam 250mg, confusion possible signs of more serious mental problemsor you develop other serious side effects, contact a doctor or other health care provider.
It may be necessary to stop taking Lariam mefloquine and use another malaria prevention medicine instead. If you can't get another medicine, leave the malaria area. However, be aware that leaving the malaria area may not protect you from getting malaria.
You still need to take a malaria prevention medicine. Who should not take Lariam mefloquine? Do not take Lariam mefloquine to prevent malaria if you have depression or had depression recently have had recent mental illness or problems, including anxiety disorderschizophrenia a severe type of mental illnessor psychosis losing touch with reality have or had seizures epilepsy or convulsions are allergic to quinine 250mg quinidine medicines related lariam Lariam mefloquine Tell your prescriber about all your medical conditions.
Lariam mefloquine may not be right for you if you generic certain conditions, especially the ones listed below: Lariam mefloquine may not be right for you. Tell your prescriber if you are pregnant or plan to become pregnant.
It is dangerous for the mother and for the unborn baby lariam to get malaria during pregnancy. Therefore, ask your prescriber if you should take Lariam mefloquine or another medicine to prevent malaria while you are pregnant. Lariam mefloquine can pass through your milk and may harm the baby, generic lariam 250mg. Therefore, lariam your prescriber whether you generic need to stop 250mg or use another medicine. Tell your prescriber about 250mg the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements.
Some medicines may give you a higher chance of having serious side effects from Lariam mefloquine.
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