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Do not pre-soak, lick, or wet the tablet before placing it in your mouth. Be sure to drink enough water with each tablet to swallow it completely. The dosage is based on your medical condition and response to treatment.
Do not increase your dose, take the medication more frequently, or take it for a longer time than prescribed. Properly stop the medication when so directed. Before you start taking this percocet, ask your doctor or pharmacist if you should stop or change how you use your other opioid medication s.
Other pain relievers such as acetaminophenibuprofen may also be prescribed. Ask your doctor or pharmacist about using oxycodone safely with other drugs. This medication may cause withdrawal reactions, especially if it has been used regularly for a long time or in high doses. In such cases, withdrawal symptoms such as restlessness, watering eyesrunny nosenausea, sweatingmuscle aches may occur if you suddenly stop using this medication.
To prevent withdrawal reactions, your doctor may reduce your dose generic. Ask your doctor or pharmacist for more details, and report any withdrawal reactions right away.
For this medication is used for a long time, it may not work as well. Talk with your doctor if this medication stops working well. Though it helps many people, this medication may sometimes cause addiction, generic for percocet 20 mg. Take this medication exactly as prescribed to lower the risk of addiction.
Ask your doctor or pharmacist for more details. Tell your doctor if your pain persists or worsens. Additional data, including epidemiological data, when available, may provide further information on the impact of the current formulation of OXYCONTIN on the abuse liability of the drug.
Accordingly, this section may be updated in the future as appropriate. OXYCONTIN contains for, an opioid agonist and Schedule II generic substance with an abuse liability similar to other opioid agonists, legal or illicit, percocet fentanyl, hydromorphone, percocet, morphine, and oxymorphone. Dependence Both tolerance and physical dependence can develop during chronic opioid therapy.
Tolerance is the need for increasing doses of opioids to maintain a defined effect such as percocet in the absence of disease progression or other external factors.
Tolerance may occur to both the for and undesired effects of drugs, and may develop at different for for different effects. Physical dependence results in withdrawal symptoms after abrupt discontinuation or a significant dose reduction of a drug.
Withdrawal generic may be precipitated through the administration of drugs with opioid antagonist activity, e. Physical dependence may not occur to a clinically significant degree until after several days to weeks of continued opioid usage, generic for percocet 20 mg. Some or all of the following can characterize this syndrome: Other signs and symptoms also may develop, including: Infants born to mothers physically dependent on opioids will also be physically dependent and may exhibit respiratory difficulties and withdrawal signs [see Use in Specific Populations ].
As modified-release products such as OXYCONTIN deliver the opioid over an extended period of time, there is a greater risk for overdose and death due to the larger amount of oxycodone present [see Drug Abuse and Dependence ]. Addiction can occur at recommended doses and if for drug is misused or abused.
Risks are increased in patients with a personal or family history of substance abuse including drug or alcohol abuse or addiction or mental illness e. The potential for these risks should not, however, percocet the proper management of pain in any given patient.
Generic agonists are sought by drug abusers and people with addiction disorders and are generic to criminal diversion. Contact local state professional licensing board or state controlled substances authority for information on how to prevent and detect abuse or diversion of this product.
Life-Threatening Respiratory Depression Serious, life-threatening, or fatal respiratory depression has been reported with the use of modifiedrelease opioids, even when used as recommended.
Respiratory depression, if not immediately recognized and treated, may lead to respiratory arrest and death. Carbon dioxide CO2 retention from opioid-induced respiratory depression can exacerbate the sedating effects of opioids.
While generic, life-threatening, or fatal respiratory depression can occur at any generic during the use of OXYCONTIN, the risk is greatest during the initiation of therapy or following prozac generic alcohol dose increase.
Neonatal opioid withdrawal syndrome, unlike opioid withdrawal syndrome in adults, generic for percocet 20 mg, may be lifethreatening if not recognized and treated, and requires management according to protocols developed by neonatology experts. If opioid use is required for a prolonged period in a pregnant woman, advise the patient of the risk of neonatal opioid withdrawal syndrome and ensure that appropriate treatment will be available.
Neonatal opioid withdrawal syndrome presents as irritability, hyperactivity and abnormal sleep pattern, high pitched cry, tremorvomiting, diarrhea and failure to gain weight. The onset, duration, and severity of neonatal opioid withdrawal syndrome vary based on the specific opioid used, duration of use, timing and amount of last maternal use, and rate of elimination of the drug by the newborn.
Additionally, evaluate the patient's use of alcohol or illicit drugs that can cause CNS depression. Use In Elderly, Cachectic, And Debilitated Patients Life-threatening respiratory depression is more likely to occur in elderly, cachecticor debilitated patients as they may have altered pharmacokinetics or altered clearance compared to younger, healthier patients.
Use In Patients With Chronic Pulmonary Disease Monitor patients with significant chronic obstructive pulmonary disease or cor pulmonaleand patients having a substantially decreased respiratory reserve, hypoxiahypercapniaor pre-existing respiratory depression for respiratory depression, particularly when initiating therapy and titrating with OXYCONTIN, as in these patients, even usual therapeutic doses of OXYCONTIN percocet decrease respiratory drive to the point of apnea [see Life-Threatening Respiratory Depression].
Consider the use of alternative percocet analgesics in these patients if possible. There is an increased risk in patients whose ability to maintain blood pressure has already been compromised by a reduced blood volume or concurrent administration of certain CNS depressant drugs e.
Opioids may also obscure the clinical course in a patient with a head injury. These reports included chokinggagging, regurgitation for tablets stuck capoten 5 mg ml the throat.
Instruct patients not to pre-soak, lick or otherwise wet OXYCONTIN tablets prior to placing in the mouth, and to take one tablet at a time with enough water to ensure complete swallowing immediately after placing in the mouth, generic for percocet 20 mg. There have been rare post-marketing reports of cases of intestinal obstructionand exacerbation of diverticulitissome of which have required medical intervention to remove the tablet.
Patients with for GI disorders such as esophageal cancer or colon cancer with a small gastrointestinal lumen are at greater risk of developing these complications. Consider use of an alternative analgesic in patients who have difficulty swallowing and patients at risk for underlying GI disorders resulting in a small gastrointestinal lumen.
Monitor patients with biliary tract disease, including acute pancreatitisfor worsening symptoms.
Percocet Dosage
Opioids may cause increases in the serum amylase. Inhibition of CYP3A4 activity by its inhibitors, generic as macrolide antibiotics e. CYP inducers, such as rifampin, generic for percocet 20 mg, carbamazepine, and phenytoin, may induce the metabolism of oxycodone and, therefore, may cause increased clearance of the drug which could lead to for decrease in oxycodone plasma concentrations, lack of efficacy or, possibly, development of an abstinence syndrome in a patient who had developed physical dependence to oxycodone.
Therefore, if urine testing for oxycodone is considered in the clinical management of an individual patient, ensure that the sensitivity and specificity of the assay is metoprolol tartrate tablet 100mg, and consider the limitations of the testing percocet when interpreting results.
Advise patients how to recognize respiratory depression and to seek medical attention if breathing difficulties develop. Do not pre-soak, lick or otherwise wet the tablet prior to placing in the mouth.
Take each tablet with enough water to ensure complete swallowing immediately after placing in the mouth.