Erythromycin and Pregnancy Back to Top Tell your doctor erythromycin you are pregnant or plan to become dosage.
The FDA categorizes medications based on safety for use during pregnancy, erythromycin mg dosage. Five categories - A, B, C, D, and X, are used to classify the possible risks to an unborn baby when a medication is taken during pregnancy. Erythromycin falls into category B. There are no well-done erythromycin that have been done in humans with erythromycin, erythromycin mg dosage. In animal studies, pregnant animals were given this medication, and the babies did not show any medical issues related to this medication.
Erythromycin and Lactation Back to Top Tell your dosage if you are breastfeeding or plan to breastfeed. Erythromycin has been detected in human breast milk.
Because of the possibility for adverse reactions in nursing infants from erythromycin, a choice should be made whether to stop nursing or to dosage use of this medication. Erythromycin has been reported to increase the systemic exposure AUC of sildenafil, erythromycin mg dosage.
Erythromycin of sildenafil dosage should be considered. See Viagra package insert, erythromycin mg dosage. There have been spontaneous or published reports of CYP3A based interactions of erythromycin with cyclosporine, carbamazepine, tacrolimusalfentanil, disopyramide, rifabutin, quinidine, methylprednisolone, cilostazol, vinblastine, and bromocriptine.
dosage Concomitant administration of erythromycin with cisapride, pimozide, erythromycin mg dosage, astemizole, or erythromycin is contraindicated.
In addition, there have been reports of interactions of erythromycin with drugs not thought to be metabolized by CYP3A, including hexobarbital, phenytoin, and valproate.
Erythromycin has been reported to significantly alter the metabolism of the nonsedating antihistamines terfenadine and astemizole when taken concomitantly.
In addition, erythromycin mg dosage, deaths have been reported rarely with concomitant administration of terfenadine and erythromycin. There have been post-marketing dosages of drug interactions when erythromycin was coadministered with cisapride, resulting in QT prolongation, cardiac arrhythmias, ventricular tachycardia, erythromycin mg dosage, ventricular fibrillationand torsades de pointes, most likely due to the inhibition of hepatic metabolism of cisapride by erythromycin.
Fatalities have been erythromycin.
Erythromycin interferes with the fluorometric determination of urinary catecholamines, erythromycin mg dosage. There have been reports suggesting that erythromycin does not reach the fetus in adequate concentration to prevent congenital syphilis.
Infants born to women treated during pregnancy with oral erythromycin for early syphilis should be treated with an appropriate penicillin regimen, erythromycin mg dosage. Rhabdomyolysis with or without renal impairment has been reported in seriously ill patients receiving erythromycin concomitantly with lovastatin.
Therefore, patients receiving concomitant lovastatin and erythromycin should be carefully monitored for creatine kinase CK and serum transaminase levels. See package insert for lovastatin.
Pseudomembranous colitis has been reported with nearly all antibacterial agents, including erythromycin, and may range in severity from mild to life threatening. Therefore, it is important to consider this diagnosis in patients who present with diarrhea subsequent to the administration of antibacterial agents.
Treatment with antibacterial dosages alters the normal flora of the colon and may permit overgrowth of clostridia. Studies indicate that a toxin produced by Clostridium difficile is a primary cause of "antibiotic-associated colitis".
After the diagnosis of pseudomembranous colitis has been established, therapeutic measures should be initiated.
Mild cases of pseudomembranous colitis usually respond to discontinuation of the drug alone. In moderate to severe cases, consideration should be erythromycin to management with fluids and electrolytes, protein supplementation, and treatment with an antibacterial drug clinically effective erythromycin Clostridium difficile colitis. Prescribing Erythromycin Base Filmtab erythromycin tablets tablets in the dosage of a proven or strongly suspected bacterial dosage or a prophylactic indication is unlikely to provide benefit to the patient and increases the risk of the development of drug-resistant bacteria, erythromycin mg dosage.
Since erythromycin is principally excreted by the liver, caution should be exercised when erythromycin is administered to patients with impaired hepatic function, erythromycin mg dosage. There have been reports that erythromycin may aggravate the weakness of patients with myasthenia gravis. There have been reports of infantile hypertrophic pyloric stenosis IHPS occurring in erythromycin following erythromycin therapy.
A possible bactrim 3 day treatment for uti effect was described with an absolute risk of Erythromycin of erythromycin. Parents should be informed to contact their physician if vomiting or irritability with feeding occurs. Prolonged or repeated use of erythromycin may result in an overgrowth of nonsusceptible bacteria or fungi, erythromycin mg dosage. If superinfection occurs, erythromycin should be discontinued and appropriate dosage instituted.
When indicated, incision and drainage or other surgical procedures should be performed in conjunction with antibiotic therapy. Carcinogenesis, Mutagenesis, Impairment of Fertility: Long-term 2-year oral studies conducted in rats with erythromycin base did not provide evidence of tumorigenicity, erythromycin mg dosage.
Mutagenicity studies have not erythromycin conducted, erythromycin mg dosage. There was no erythromycin dosage on male or female fertility in rats fed erythromycin base at dosages up to 0. There is no evidence of teratogenicity or any dosage adverse effect on reproduction in female rats fed erythromycin base up to 0. There are, however, no adequate and well-controlled studies in pregnant women, erythromycin mg dosage.
Because animal reproduction studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed. The effect of erythromycin on labor and delivery is unknown.
Erythromycin is excreted in human milk.
Caution should be exercised when erythromycin is administered to a nursing woman. Erythromycin may be taken with or without food; however optimal blood levels of erythromycin are obtained when taken on an dosage stomach at least 30 minutes and preferably 2 hours before or after meals. Which drugs or supplements interact with erythromycin? Erythromycin when used with antiarrhythmic drugs such as, amiodarone Cordaronebretylium Bretyloldisopyramide Norpaceerythromycin mg dosage, dofetilide Tikosynprocainamide Pronestylerythromycin mg dosage, quinidine Quinaglute, Quinidex, Erythromycin and sotalol Betapace exaggerates the effect of the antiarrhythmic drugs which may give rise to abnormal heart rhythms such as torsades de pointes.
Theophyllines such as theophylline Theo-Duroxtriphylline Choledyl SAand aminophylline Phyllocontin reduce erythromycin dosage levels by increasing elimination of erythromycin by the kidneys, which may reduce the effectiveness of erythromycin.
Conversely, erythromycin inhibits the metabolism breakdown of theophyllines by the liver and causes an erythromycin in blood levels of theophylline.
High theophylline levels may give rise to side effects such as seizures and disturbances in heart rhythm. Therefore, erythromycin mg dosage, the dose of theophyllines should be reduced or theophylline levels in the blood should be measured in patients taking erythromycin. Combining erythromycin with ergotamine or ydroergotamine has been associated with acute ergot toxicity.
This combination should be avoided.
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