Sumatriptan 50mg tablets
Sumatriptan Oral Tablet | Side Effects, Dosage, Uses & More
Overdose: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call Otherwise, call a poison control center right away. US residents can call their local poison control center at Canada residents can call a provincial poison control center.
Certain forms of migraine cannot be treated with sumatriptan.
sumatriptan tablet - oral, Imitrex
How to take Sumatriptan Tablets Always take this medicine exactly as your doctor or pharmacist has told you, sumatriptan 50mg tablets. Check with your doctor or pharmacist if you are not sure.
After taking Sumatriptan you may feel pain in your chest and a feeling of pressure for a short time. This can be quite intensive and may radiate up towards your throat. In very rare cases this may be caused by effects on your heart.
Therefore, if the symptoms do not disappear, sumatriptan 50mg tablets, contact your doctor. How to take Sumatriptan Tablets Always take this medicine exactly as your tablet has told you. Check with your doctor or pharmacist if you are not sure. Swallow each tablet whole with water, sumatriptan 50mg tablets. Do not chew or sumatriptan them. When to take Sumatriptan Tablets It is tablet to take these tablets as soon as 50mg feel a migraine coming on, although-you can take it at any time during an attack Do not use these tablets to try to prevent an attack-only use it after your 50mg symptoms start.
How much to take Adults aged 18 to 65 Viagra 10mg cena usual sumatriptan for adults aged 18 to 65 is one 50mg tablet, swallowed whole with water.
Children under 18 This medicine is not recommended for children under 18 years old. Elderly aged over 65 This medicine is not recommended for people aged over If your symptoms start to come back You can take a second tablet if at least 2 hours have passed since the first tablet. Do not take more than mg in total in 24 hours.
If the first tablet has no effect Do not take a second tablet or any other Sumatriptan Tablets preparation for the same attack. Sumatriptan Tablets can still be used for your next attack. If these tablets do not give you any relief: Ask your doctor or pharmacist for advice. Taking too much Sumatriptan Tablets could make you ill.
If you have taken more than mg in 24 hours: Contact your doctor for advice. Advertisement Take as directed Take as directed Sumatriptan oral tablet is used for 50mg treatment. Your symptoms of tablet or cluster headaches may not improve. If you take too much: You could have dangerous levels of the drug in your body. Symptoms of an overdose of this drug can include: If your symptoms are severe, call or go to the nearest emergency room right away, sumatriptan 50mg tablets.
How to tell if the drug is working: Ischemic cardiac syndromes include, but are not limited to, angina pectoris of any type e. Cerebrovascular syndromes include, but are not limited to, strokes of any type as well as transient ischemic attacks. It is strongly recommended that sumatriptan not be given to patients in whom unrecognized CAD is predicted by the presence of risk factors e. The sensitivity of cardiac diagnostic procedures to detect cardiovascular disease or predisposition to coronary artery vasospasm is modest, at best, sumatriptan 50mg tablets.
Because cardiac ischemia can occur in sumatriptan absence of clinical symptoms, consideration should be given to obtaining on the first occasion of use an electrocardiogram ECG during the interval immediately following IMITREX Tablets in these patients with risk factors, sumatriptan 50mg tablets.
It is recommended that patients who are intermittent long-term users of sumatriptan sumatriptan who have or acquire risk factors predictive of CAD, as described above, mirtazapine uk buy periodic interval cardiovascular evaluation as they continue to use sumatriptan.
The systematic approach described above is intended to reduce the likelihood that patients with unrecognized cardiovascular disease will be inadvertently exposed to sumatriptan. Considering the extent of use of sumatriptan in patients with migraine, the incidence of these events is extremely low. The fact that sumatriptan can 50mg coronary vasospasm, that some of these events have occurred in patients with no prior cardiac disease history and with documented absence of CAD, sumatriptan 50mg tablets, and the close 50mg of the events to sumatriptan use support the conclusion that some of these cases were caused by the drug.
In many cases, however, where there has been known underlying coronary artery disease, the relationship is uncertain. Premarketing Experience With Sumatriptan Of 6, patients with migraine who participated in premarketing controlled and uncontrolled clinical trials of oral sumatriptan, 2 experienced clinical adverse events shortly after receiving oral sumatriptan that may have reflected coronary vasospasm.
Neither of these adverse events was associated with a serious clinical outcome. Among the more than 1, patients with migraine who participated in premarketing controlled clinical trials sumatriptan subcutaneous sumatriptan, there were 8 patients who sustained clinical events during or shortly after receiving sumatriptan that may have reflected coronary artery vasospasm.
Six of these 8 tablets had ECG changes consistent with transient ischemia, but without accompanying clinical symptoms or signs.
It should be noted that migraineurs may be at increased risk of certain cerebrovascular events e. Following administration, sumatriptan can be associated with transient symptoms including chest pain and tightness, which may be intense and involve the throat see tablet 4. Where such symptoms are thought to indicate ischaemic heart disease, no further doses of sumatriptan should be given, and an appropriate evaluation should be carried out. There have been rare post-marketing reports describing patients with serotonin syndrome including altered mental status, autonomic instability and neuromuscular abnormalities following the use of a selective serotonin reuptake inhibitor SSRI and sumatriptan.
Serotonin syndrome has been reported following concomitant treatment with triptans and serotonin noradrenaline reuptake inhibitors SNRIs, sumatriptan 50mg tablets. Sumatriptan should be administered with caution to patients with conditions that may affect significantly the absorption, sumatriptan 50mg tablets, metabolism or excretion of the drug, e. Sumatriptan should be used with caution in patients with a history of seizures or other risk factors which lower the seizure threshold, as seizures have been reported in association with sumatriptan see section 4.
50mg with known hypersensitivity to sulphonamides may exhibit an pristiq zoloft comparison reaction following administration of sumatriptan. Reactions may range from cutaneous hypersensitivity to anaphylaxis. Evidence of cross sensitivity is sumatriptan, however, caution should be exercised before using sumatriptan in these patients.
The Cmax is similar during a migraine attack and during a migraine-free tablet, but the Tmax is slightly later during the attack, approximately 2. The effect of Sumatriptan on the protein binding of other drugs has not been evaluated.
The apparent volume of distribution is 2. In vitro studies with human microsomes suggest that Sumatriptan is metabolized by MAO, predominantly the A isoenzyme. Most of a radiolabeled dose of Sumatriptan excreted in the urine is the major metabolite 50mg acetic tablet IAA or the IAA glucuronide, both pamelor 50mg engorda which are inactive.
Most of the radiolabeled compound excreted in sumatriptan urine is the major 50mg, indole acetic acid IAAsumatriptan 50mg tablets, which is inactive, or the IAA glucuronide.
The pharmacokinetics of Sumatriptan in the elderly mean age: The effect of renal impairment on the pharmacokinetics of Sumatriptan has not been examined. The tablet plays an important role in the presystemic clearance of orally administered Sumatriptan. Accordingly, the bioavailability of Sumatriptan following oral administration may be markedly increased in patients with liver disease. The pharmacokinetics of Sumatriptan in patients with severe sumatriptan impairment has not been studied.
The use of Sumatriptan succinate tablets in this population is contraindicated [see Contraindications 4 and Use in Specific Populations 8.
In a trial comparing females to males, sumatriptan 50mg tablets, no pharmacokinetic differences were observed between genders for AUC, Cmax, Tmax, and half-life.