Ask your doctor when to start or stop taking this medication. Tell your doctor or pharmacist if you are taking other products that cause drowsiness such as opioid pain or cough relievers such as codeine, hydrocodone , alcohol, marijuana , drugs for sleep or anxiety such as alprazolam , lorazepam , zolpidem , muscle relaxants such as carisoprodol , cyclobenzaprine , or antihistamines such as cetirizine , diphenhydramine.

Check the labels on all your medicines such as allergy or cough -and-cold products because they may contain ingredients that cause drowsiness. Ask your pharmacist about using those products safely. Some products have ingredients that could raise your heart rate or blood pressure.

Tell your pharmacist what products you are using, and ask how to use them safely especially cough -and-cold products or diet aids. Caffeine can increase the side effects of this medication. Avoid drinking large amounts of beverages containing caffeine coffee, tea, colas or eating large amounts of chocolate.

Make sure laboratory personnel and all your doctors know you use this drug. This document does not contain all possible interactions.

Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist. Does Phentermine HCL interact with other medications? Overdose If someone has overdosed and has serious symptoms such as passing out or trouble breathing , call Otherwise, call a poison control center right away. US residents can call their local poison control center at Canada residents can call a provincial poison control center.

Symptoms of overdose may include: Notes Appetite suppressants should not be used in place of proper diet. For best results, this drug must be used along with a doctor-approved diet and exercise program.

Do not share this medication with others. It is against the law. Consult your doctor for more details. Ignoring it has not made it go away, thinking about it freaks me right out.

Do not let shame kill your quality of life any longer. I truly, truly hope you can beat this, I haven't been able to. And the future looks dark and bleak for me. The whole thing feels silly at times I hope you find a way. I first started because I would get a lot of headaches. I don't take as many as you do, but I have to write down which drugstore and the date I bought them so they don't ask questions. The problem now is that if I don't take them I get headaches and I feel so tired and confused.

I'm trying so hard to stop, but it's never a good time, I always find an excuse to take some for the last day Is there something that we can take to help get off these things? Reply Cheryl December 24th, I have been prescribed for up to mg a day 2 pills every four hours sometimes take 3 Or 4 at a time but then take no more during the day so I am given pills a month for fibromyalgia pain, I also take a slow release tramadol once a day Reply Cheryl December 24th, Sorry I am also a alcohol abuser who is getting better and was going to go to a treatment center but husband got diagnosed with a terminal cancer so my role has become caretaker so I need to be sober and trustworthy in case I need to quickly get him to the hospital Reply Cheryl December 24th, Oops also forgot the 4 mg of lorazepam 4 times daily and sometimes I take all 4 at one time because 1 does not seem to do a thing.

Reply Lesley January 18th, Hi folks, been reading your comments and I am shocked to see just how many do suffer from codeine addiction. I have been taking dyhydrocodiene now for 28yrs. Initially my daily dose rose to approx. The thing that people don't understand about codeine addiction is that because it suppresses the central nervous system, most internal problems are also masked.

I have recently reduced down to 10 but due to my having an inherent and serious heart condition from both parents, I hadn't realized the entire time I had been displaying serious painful symptoms which normally would've triggered me to see my cardiologist i.

When then I reduced my symptoms as with all sorts of other symptoms became apparent with the less dosage I took the less nervous system suppression. I found out my life had been at serious risk because I hadn't felt the symptoms my body was giving out due to suppression.

Once I reduced as I said, it became apparent my heart condition had worsened but I just didn't know. I have to do this at a super slow rate. I have successfully kicked my habit twice before for a very short period only to stupidly end up back on them an without sounding arrogant, there is nothing I don't know about codeine or its withdrawals from every single angle as I have the T-shirt and video the lot.

If it helps, people can inbox me for advice and I will gladly give my phone number to best advice you safely and without risks as with available professional sources out there to also help. I actually believe I have a rock solid answer to coming off this drug with the least physical and emotional impact and if I can help one person to get where I am today from a place where my body expected a dose almost to the clock, to now controlling it as opposed to it controlling me I have halved my dose very easily which at one time the thought of reducing just one scared the living daylights out of me.

It has to be done individually to each person and not on a statistical all for one regime. Please refer to the author of this page for my email which I gladly give consent for them to do.

It will be easier to talk on the phone than email lots of people hence why receiving your email I will contact you back or vice versa. Good luck with your journey guys. But it's the Tylenol I'm worried about. How am I still alive? I quit coke and heroin cold turkey and suffered through it, but I can't quite T1's. What the hell do I do? I have an appt. Tried to quit several times I have to do something before my liver explodes Reply Anika March 12th, I have been on Panadeine forte for at least 10 years, with Endone and Tramadol interspersered here and there.

I don't know HOW addicted I am, although I can certainly relate to the taking it at times even when not in pain to get that calm feeling.

I have been concerned by the long term side effects, and as a personal way of managing any liver damage Its primary action is liver support.

It helps create NEW liver cells which replace the dead ones. Sometimes hopelessness sets in when you feel you don't know where to go. Most Doctors don't know much about alternatives for pain management. My own regimen is going to be have started , is researching anti-inflammatory foods, strengthening exercise, intake of silymarin, and changing my stinking thinking about myself and treasuring my body.

Good luck to everyone and may you all be set free from this bondage, Life is worth living and you are a blessing! Reply Chris April 4th, I'm on day 11 on quitting my codeine addiction and it's become manageable with the withdraw symptoms, I have been off and on for close to 7 years but now I have a baby boy to quit for and for the first time since I quit I was tested when my wife said she wouldn't think less of me if I bought painkillers for my eye watering toothache I currently have, just as long as I don't go on for more than 3 days.

I said no, the toothache is bad but I don't want that feeling anymore that codeine gives me. I feel for anyone on this terrible addiction and know the awful things it does to us all, I sneaked around trying to find money, spending all our wages on painkillers, I would lie in the chemist saying I had back ache or toothache or even worse "it's for my wife" I even got banned from a pharmacy just round the corner from me, it was a horrible feeling for the manager to come out to ask me questions in front of everyone but now I'm free and on my baby boys life I will never be hooked on this curse again.

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What are the possible side-effects? As with all medicines, opioids have a number of possible side-effects. In general, the stronger the opioid, the more likely you are to have side-effects. The most common side-effects are constipation, feeling sick nausea and drowsiness. Constipation - when you start treatment with an opioid, your doctor will usually also prescribe a laxative. Laxatives help to ease and prevent constipation by softening the poo stools , making it easier to pass, or they stimulate your bowel to push the stools along more quickly.

Nausea - feeling sick is a common side-effect when you first start taking an opioid. This usually passes after a week or so, once your body gets used to this medicine. Your doctor will prescribe an anti-sickness medicine an anti-emetic if you feel sick. Tell your doctor if sickness lasts for more than a week.

Codeine and its metabolites are excreted almost entirely by the kidney, mainly as conjugates with glucuronic acid.

Relation to other opioids[ edit ] Codeine has been used in the past as the starting material and prototype of a large class of mainly mild to moderately strong opioids; such as hydrocodone in Germany , oxycodone in Germany , dihydrocodeine in Germany , and its derivatives such as nicocodeine in Austria. In general, the various classes of morphine derivatives such as ketones, semisynthetics like dihydromorphine , halogeno-morphides, esters, ethers, and others have codeine, dihydrocodeine, and isocodeine analogues.

As an analgesic, codeine compares weakly to other opiates. Related to codeine in other ways are codoxime , thebacon , codeine-N-oxide genocodeine , related to the nitrogen morphine derivatives as is codeine methobromide, and heterocodeine , which is a drug six times stronger than morphine and 72 times stronger than codeine due to a small re-arrangement of the molecule, viz.

Drugs bearing resemblance to codeine in effects due to close structural relationship are variations on the methyl groups at the 3 position including ethylmorphine a. While having no narcotic effects of its own, the important opioid precursor thebaine differs from codeine only slightly in structure. Pseudocodeine and some other similar alkaloids not currently used in medicine are found in trace amounts in opium as well.

History[ edit ] Codeine, or 3-methylmorphine, is an alkaloid found in the opium poppy , Papaver somniferum var. Opium poppy has been cultivated and utilized throughout human history for a variety of medicinal analgesic, anti-tussive and anti-diarrheal and hypnotic properties linked to the diversity of its active components, which include morphine, codeine and papaverine.

Until the beginning of the 19th century, raw opium was used in diverse preparations known as laudanum see Thomas de Quincey 's " Confessions of an English Opium-Eater ", and paregoric elixirs , a number of which were popular in England since the beginning of the 18th century; the original preparation seems to have been elaborated in Leiden , the Netherlands around by a chemist named Lemort; in the London Pharmocopeia mentions an Elixir Asthmaticum, replaced by the term Elixir Paregoricum "pain soother" in The progressive isolation of opium's several active components opened the path to improved selectivity and safety of the opiates-based pharmacopeia.

This paved the way for the elaboration of a new generation of safer, codeine-based specific antitussive and antidiarrheal formulations. Codeine is currently the most widely used opiate in the world, [37] [38] and is one of the most commonly used drugs overall according to numerous reports by organizations including the World Health Organization and its League of Nations predecessor agency.

It is one of the most effective orally administered opioid analgesics and has a wide safety margin. While codeine can be directly extracted from opium, its original source, most codeine is synthesized from the much more abundant morphine through the process of O- methylation , [38] [39] through a process first completed in the late 20th century by Robert C.

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