You are pregnant or planning to become pregnant. If so, tell your doctor immediately You have recently given birth, had a miscarriage or an abortion You have premenstrual problems or non-cancerous breast disease You have a non-cancerous tumour. You may need a full medical check-up first. Do not give Parlodel to children under 7 years old. These are called impulse control disorders and can include behaviours such as addictive gambling, excessive eating or spending, and abnormally high sex drive or an increase in sexual thoughts or feelings.
Your doctor may need to adjust or stop your dose. Tell your doctor if you are taking any of the following medicines: Taking Parlodel with food and drink You must take this medicine with a meal. In these cases the visual field defect may improve on reduction of bromocriptine dosage while there is some elevation of prolactin and some tumour re-expansion. Monitoring of visual fields in patients with macroprolactinoma is therefore recommended for an early recognition of secondary field loss due to chiasmal herniation and adaptation of drug dosage.
The data available suggest that this may result from shrinkage of invasive tumours. Bromocriptine has been associated with somnolence and episodes of sudden sleep onset, particularly in patients with Parkinson's disease. Sudden onset of sleep during daily activities, in some cases without awareness or warning signs, has been reported very rarely.
Patients must be informed of this and advised to exercise caution while driving or operating machines during treatment with bromocriptine. Furthermore, a reduction of dosage or termination of therapy may be considered.
This is in order to avoid suppression of prolactin to below normal levels, with consequent impairment of luteal function. Six monthly assessment is suggested for post-menopausal women and annual assessment for women with regular menstruation. A few cases of gastrointestinal bleeding and gastric ulcer have been reported. Patients with a history of evidence of peptic ulceration should be closely monitored when receiving the treatment. Since, especially during the first few days of treatment, hypotensive reactions may occasionally occur and result in reduced alertness, particular care should be exercised when driving a vehicle or operating machinery.
Symptoms of overdose may include: Notes Do not share this medication with others. Consult your doctor for more details. People with Parkinson's disease may have an increased risk for developing skin cancer melanoma. If you are taking this drug to treat Parkinson's disease , tell your doctor promptly if you notice a change in the appearance or size of moles or other unusual skin changes.
Ask your doctor if you should have regular skin exams. Missed Dose If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip themissed dose and resume your usual dosing schedule. Do not double the dose to catch up. Storage Store at room temperature away from light and moisture. Do not store in the bathroom.
Keep all medications away from children and pets. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company. Information last revised July Warnings and precautions Talk to your doctor before taking Bromocriptine if You have just given birth as you may be more at risk of certain conditions.
These are very rare but may include high blood pressure, heart attack, convulsions, stroke or mental problems. Therefore your doctor will need to check your blood pressure regularly during the first days of treatment. Speak immediately to your doctor if you experience high blood pressure, chest pain or unusually severe or persistent headache, with or without vision problems.
You have, or have ever had stomach ulcers and bleeding You have liver disease You have, or have ever had a condition called fibrosis. Fibrosis causes thickening and stiffening of the heart, lungs and abdomen which can stop them working properly. Before you are given Bromocriptine your doctor will check that your heart, lungs and kidneys are in good condition.
The doctor may also do an ultrasound an echocardiogram of your heart for check for scar tissue You are pregnant or planning to become pregnant. If so, tell your doctor immediately You have recently given birth, had a miscarriage or an abortion You have premenstrual problems or non-cancerous breast disease You have a non-cancerous tumour. You may need a full medical check-up first. Do not give Bromocriptine to children under 7 years old. These are called impulse control disorders and can include behaviours such as addictive gambling, excessive eating or spending, and abnormally high sex drive or an increase in sexual thoughts or feelings.
Your doctor may need to adjust or stop your dose. Tell your doctor if you are taking any of the following medicines: These are very rare but may include high blood pressure, heart attack, convulsions, stroke or mental problems. Therefore your doctor will need to check your blood pressure regularly during the first days of treatment. Speak immediately to your doctor if you experience high blood pressure, chest pain or unusually severe or persistent headache, with or without vision problems.
Fibrosis causes thickening and stiffening of the heart, lungs and abdomen which can stop them working properly. Before you are given Parlodel your doctor will check that your heart, lungs and kidneys are in good condition. If so, tell your doctor immediately 3. Some cases of strokes and seizures were also preceded by visual disturbances blurred vision, and transient cortical blindness.
Nine cases of acute myocardial infarction have been reported. Although a causal relationship between bromocriptine mesylate administration and hypertension, seizures, strokes, and myocardial infarction in postpartum women has not been established, use of the drug for prevention of physiological lactation, or in patients with uncontrolled hypertension is not recommended.
When bromocriptine mesylate is being used to treat acromegaly or Parkinson's disease in patients who subsequently become pregnant, a decision should be made as to whether the therapy continues to be medically necesssary or can be withdrawn.
Because of the possibility of an interaction between bromocriptine mesylate and other ergot alkaloids, the concomitant use of these medications is not recommended. Particular attention should be paid to patients who have recently received other drugs that can alter the blood pressure. Periodic monitoring of the blood pressure, particularly during the first weeks of therapy is prudent.
If hypertension, severe, progressive, or unremitting headache with or without visual disturbance , or evidence of CNS toxicity develops, drug therapy should be discontinued and the patient should be evaluated promptly. In those instances in which bromocriptine mesylate treatment was terminated, the changes slowly reverted towards normal.
Care should be exercised when administering bromocriptine mesylate therapy concomitantly with other medications known to lower blood pressure. The drug should be used with caution in patients with a history of psychosis or cardiovascular disease. If acromegalic patients or patients with prolactinoma or Parkinson's disease are being treated with bromocriptine mesylate during pregnancy, they should be cautiously observed, particularly during the post-partum period if they have a history of cardiovascular disease.
Hyperprolactinemic States The relative efficacy of bromocriptine mesylate versus surgery in preserving visual fields is not known. Patients with rapidly progressive visual field loss should be evaluated by a neurosurgeon to help decide on the most appropriate therapy. Patients not seeking pregnancy, or those harboring large adenomas, should be advised to use contraceptive measures, other than oral contraceptives, during treatment with bromocriptine mesylate.
Since pregnancy may occur prior to reinitiation of menses, a pregnancy test is recommended at least every four weeks during the amenorrheic period, and, once menses are reinitiated, every time a patient misses a menstrual period.
Treatment with bromocriptine mesylate tablets should be discontinued as soon as pregnancy has been established. Patients must be monitored closely throughout pregnancy for signs and symptoms that may signal the enlargement of a previously undetected or existing prolactin-secreting tumor.
Discontinuation of bromocriptine mesylate treatment in patients with known macroadenomas has been associated with rapid regrowth of tumor and increase in serum prolactin in most cases. Acromegaly Cold sensitive digital vasospasm has been observed in some acromegalic patients treated with bromocriptine mesylate. The response, should it occur, can be reversed by reducing the dose of bromocriptine mesylate and may be prevented by keeping the fingers warm.
Cases of severe gastrointestinal bleeding from peptic ulcers have been reported, some fatal. Although there is no evidence that bromocriptine mesylate increases the incidence of peptic ulcers in acromegalic patients, symptoms suggestive of peptic ulcer should be investigated thoroughly and treated appropriately. Patients with a history of peptic ulcer or gastrointestinal bleeding should be observed carefully during treatment with bromocriptine mesylate.
Possible tumor expansion while receiving bromocriptine mesylate therapy has been reported in a few patients. Since the natural history of growth hormone secreting tumors is unknown, all patients should be carefully monitored and, if evidence of tumor expansion develops, discontinuation of treatment and alternative procedures considered.
Do not share this medication with others. Hypotension and syncope may occur more frequently during initial therapy or with an increase in dose at any time. Patients must be informed of this and advised to exercise tablet while cetirizine 40mg daily or operating machines during treatment with bromocriptine. It bromocriptine improve your ability to move and can decrease shakiness tremorstiffness, slowed movement, and unsteadiness. Before you take Parlodel 3. Get OFF your first medications! If so, tell your doctor immediately 3. Side effects can be mild or severe, temporary or permanent, bromocriptine mesylate 2.5mg tablets. Driving and using machines You must not drive or operate machines if you feel dizzy or faint. If it is near the time of mesylate next dose, skip themissed dose and resume your usual bromocriptine schedule. 2.5mg is an ergot medication that works by acting like a certain natural substance dopamine in the brain. This will help the body adjust to the new medicine and stop you or your child from getting so many side effects. The main route of excretion of the drug is via the bile, only mesylate. Bromocriptine is not 2.5mg for stopping unwanted breast milk after pregnancy, miscarriage, or abortion because of tablet serious side effects such as high blood pressure, seizure, heart attack, stroke.
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