Minor Although desloratadine is considered a 'non-sedating' antihistamine, dose-related sedation has been noted. For this reason, it would be prudent to monitor for drowsiness during concurrent use of desloratadine with CNS depressants such as other H1-blockers.
Acetaminophen; Caffeine; Phenyltoloxamine; Salicylamide: Acetaminophen; Chlorpheniramine; Dextromethorphan; Phenylephrine: Acetaminophen; Chlorpheniramine; Dextromethorphan; Pseudoephedrine: Acetaminophen; Chlorpheniramine; Phenylephrine; Phenyltoloxamine: For this reason, it would be prudent to monitor for drowsiness when used concurrently with other CNS depressants such as benzodiazepines.
For this reason, it would be prudent to monitor for drowsiness or dizziness when used concurrently with other CNS depressants such as tricyclic antidepressants. Minor Plasma concentrations of desloratadine may be elevated when administered concurrently with cobicistat. Clinical monitoring for adverse effects, such as CNS effects, is recommended during coadministration.
Cobicistat is a P-glycoprotein P-gp inhibitor, while desloratidine is a P-gp substrate. Use caution during coadministration. Atropine; Hyoscyamine; Phenobarbital; Scopolamine: Minor Desloratadine is a substrate of P-glycoprotein P-gp and azithromycin is a P-gp inhibitor; therefore, desloratadine concentrations could be increased with coadministration.
Monitor patients for increased side effects if these drugs are given together. Belladonna Alkaloids; Ergotamine; Phenobarbital: Moderate Close clinical monitoring is advised when administering desloratadine with boceprevir due to an increased potential for desloratadine-related adverse events.
If desloratadine dose adjustments are made, re-adjust the dose upon completion of boceprevir treatment. Although this interaction has not been studied, predictions about the interaction can be made based on the metabolic pathway of desloratadine. Desloratadine is a substrate of the drug efflux transporter P-glycoprotein PGP ; boceprevir is an inhibitor of this efflux protein.
Coadministration may result in elevated desloratadine plasma concentrations. Minor Monitor for an increase in desloratadine-related adverse events if concomitant use with cabozantinib is necessary, as plasma concentrations of desloratadine may be increased. Cabozantinib is a P-glycoprotein P-gp inhibitor and desloratadine is a substrate of P-gp in vitro; the clinical relevance of this finding is unknown. Minor Increased concentrations of desloratadine may occur if it is coadministered with carvedilol; exercise caution.
Carvedilol is a P-glycoprotein P-gp inhibitor and desloratadine is a P-gp substrate. Chlorpheniramine; Guaifenesin; Hydrocodone; Pseudoephedrine: For this reason, it would be prudent to monitor for drowsiness when used concurrently with other CNS depressants such as antipsychotics. Cobicistat; Elvitegravir; Emtricitabine; Tenofovir Alafenamide: Minor Use caution when administering conivaptan and desloratadine concurrently.
Conivaptan is an inhibitor of P-glycoprotein P-gp. Co-administration of conivaptan with P-gp substrates, such as desloratadine, can increase desloratadine exposure leading to increased or prolonged therapeutic effects and adverse events. Minor Concomitant use of crizotinib and desloratadine may result in increased desloratadine concentrations.
Monitor patients for toxicity with coadministration. Minor Systemic exposure of desloratadine, a P-glycoprotein P-gp substrate, may be increased when administered concurrently with daclatasvir, a P-gp inhibitor. Taking these drugs together could increase or prolong the therapeutic effects of desloratadine; monitor patients for potential adverse effects.
Dasabuvir; Ombitasvir; Paritaprevir; Ritonavir: Minor The plasma concentrations of desloratadine may be elevated when administered concurrently with dasabuvir; ombitasvir; paritaprevir; ritonavir. Ritonavir and paritaprevir are P-glycoprotein P-gp inhibitorsis a P-glycoprotein P-gp inhibitor, while desloratidine is a P-gp substrate.
Minor The plasma concentrations of desloratadine may be elevated when administered concurrently with ritonavir. Ritonavir is a P-glycoprotein P-gp inhibitor, while desloratadine is a P-gp substrate.
For this reason, it would be prudent to monitor for drowsiness during concurrent use of desloratadine with CNS depressants such as ethanol. Desloratadine is a P-glycoprotein substrate. Increased concentrations of desloratadine may occur if it is coadministered with etravirine; exercise caution.
Moderate Caution is advised when administering desloratadine with fosamprenavir, as concurrent use may result in reduced desloratadine plasma concentrations. Desloratadine is a substrate for the drug transporter P-glycoprotein P-gp. What will it do for me? Desloratadine belongs to a group of medications known as antihistamines, specifically the class known as H1-receptor antagonists.
During an allergic reaction, the body produces a chemical called histamine, which causes allergy symptoms such as hives, runny nose, sneezing, itchy throat, congestion, and itchy watery eyes. Desloratadine works by blocking the action of histamine in the body. This medication is used to relieve the symptoms of seasonal and year-round allergies including nasal congestion, sneezing, runny nose, itchy nose, itchy palate, coughing, and itchy watery red eyes. It is also use to relieve the symptoms of allergic skin conditions e.
Desloratadine usually starts to work within 75 minutes and lasts for 24 hours. Any specific brand name of this medication may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of this medication may not be used for all of the conditions discussed here. Your doctor may have suggested this medication for conditions other than those listed in these drug information articles.
If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor. Do not give this medication to anyone else, even if they have the same symptoms as you do.
It can be harmful for people to take this medication if their doctor has not prescribed it. What form s does this medication come in? Each blue, round, coated tablet, debossed with a "D" on one side of the tablet, contains 5 mg desloratadine. How should I use this medication?
It may be taken with or without food. Do not increase your dose or take this medication more often than directed. Tell your doctor if your condition does not improve or if it worsens. What conditions does Desloratadine treat? Side Effects Sore throat , nausea , tiredness, stomach upset, or muscle pain may occur.
Fever, loss of appetite, diarrhea , or trouble sleeping may also occur, especially in children. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction , including: This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US - Call your doctor for medical advice about side effects. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at List Desloratadine side effects by likelihood and severity. Precautions Before taking desloratadine, tell your doctor or pharmacist if you are allergic to it; or to loratadine ; or if you have any other allergies.
This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication , tell your doctor or pharmacist your medical history, especially of: Desloratadine does not usually cause drowsiness when used at recommended doses.
Cases of palpitations, rapid heartbeat, stomach pain, nausea feeling sickvomiting, upset stomach, diarrhoea, dizziness, tab, inability to sleep, muscle pain, hallucinations, seizures, tab with increased body movement, liver inflammation and abnormal liver function tests have desloratadine been reported very rarely, desloratadine tabs 5mg. Who should NOT take this medication? Rarely, a loculated apical pneumothorax or effusion may require placement of an anterior tube in the tab in- tercostal space at the midclavicular line, desloratadine tabs 5mg. The results of a population pharmacokinetic analysis indicated that a 5mg of 1 mg for subjects aged 5mg to 11 months and 1. Any specific brand name of this medication may not be available in all of the forms or approved for all of desloratadine conditions discussed here. Liver disease treatments Some doctors advocate regular monitoring of liver Resources function in elderly patients with alpha-1 antitrypsin. 5mg you become pregnant while taking this medication, contact your minocycline for sale online immediately. Do not take extra medicine to make up the missed dose. If you become pregnant, contact your doctor. Artifacts and pitfalls Although desloratadine data can be acquired with perfusion Desloratadine tab desloratadine 5 mg on line allergy medicine rite aid, the accuracy of 5mg flow values obtained has not been fully validated purchase desloratadine 5 mg on line allergy gluten, desloratadine tabs 5mg.
All medicines may 5mg side effects, desloratadine tabs 5mg, but many people have no, or minor, side effects. To take the orally disintegrating tab, use dry hands to peel back the foil packaging. Desloratadine is used for treating allergy symptoms and tab hives, desloratadine tabs 5mg. Liver disease treatments Some doctors advocate regular monitoring of liver Resources function in elderly patients with alpha-1 antitrypsin. Do not store in the bathroom. In these studies, no overall differences in safety were observed between poor desloratadine and normal metabolizers. Do not dispose of medications in wastewater e, desloratadine tabs 5mg. Use in children and adolescents Do not give this medicine to children less than 12 tabs of 5mg. Symptoms of overdose may include: How is it used? There is no need to download another app! Unless 5mg doctor tells you otherwise, continue your normal diet. Many of these side effects can 5mg managed, desloratadine tabs 5mg, and some may go away on their own over time. It works by stopping histamine from joining with receptors, and initiating an allergic reaction to pollen and dust. Do not desloratadine, stop, or change the dosage of any medicines without your doctor's approval. Many people using desloratadine medication do not have serious tab desloratadine.
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