Hypertoxin producing strains of C. CDAD must be considered in all patients who present with diarrhea following antibiotic use. Careful medical history is necessary since CDAD has been reported to occur over two months after the administration of antibacterial agents. Appropriate fluid and electrolyte management, protein supplementation, antibiotic treatment of C. Because azithromycin is principally eliminated via the liver, caution should be exercised when azithromycin is administered to patients with impaired hepatic function.
Prolonged cardiac repolarization and QT interval, imparting a risk of developing cardiac arrhythmia and torsades de pointes, have been seen in treatment with other macrolides. A similar effect with azithromycin cannot be completely ruled out in patients at increased risk for prolonged cardiac repolarization.
Exacerbation of symptoms of myasthenia gravis and new onset of myasthenic syndrome have been reported in patients receiving azithromycin therapy.
Prescribing azithromycin tablet in the absence of a proven or strongly suspected bacterial infection or a prophylactic indication is unlikely to provide benefit to the patient and increases the risk of the development of drug-resistant bacteria.
Azithromycin tablets and oral suspension can be taken with or without food. Patients should also be cautioned not to take aluminum- and magnesium-containing antacids and azithromycin simultaneously. The patient should be directed to discontinue azithromycin immediately and contact a physician if any signs of an allergic reaction occur. Patients should be counseled that antibacterial drugs including azithromycin tablets should only be used to treat bacterial infections.
They do not treat viral infections e. When azithromycin tablets are prescribed to treat a bacterial infection, patients should be told that although it is common to feel better early in the course of therapy, the medication should be taken exactly as directed.
Skipping doses or not completing the full course of therapy may 1 decrease the effectiveness of the immediate treatment and 2 increase the likelihood that bacteria will develop resistance and will not be treatable by azithromycin tablet or other antibacterial drugs in the future. Diarrhea is a common problem caused by antibiotics which usually ends when the antibiotic is discontinued.
Sometimes after starting treatment with antibiotics, patients can develop watery and bloody stools with or without stomach cramps and fever even as late as two or more months after having taken the last dose of the antibiotic. If this occurs, patients should contact their physician as soon as possible. Co-administration of nelfinavir at steady-state with a single oral dose of azithromycin resulted in increased azithromycin serum concentrations. Although a dose adjustment of azithromycin is not recommended when administered in combination with nelfinavir, close monitoring for known side effects of azithromycin, such as liver enzyme abnormalities and hearing impairment, is warranted.
Although, in a study of 22 healthy men, a 5-day course of azithromycin did not affect the prothrombin time from a subsequently administered dose of warfarin, spontaneous post-marketing reports suggest that concomitant administration of azithromycin may potentiate the effects of oral anticoagulants.
Prothrombin times should be carefully monitored while patients are receiving azithromycin and oral anticoagulants concomitantly. Drug interaction studies were performed with azithromycin and other drugs likely to be coadministered. Co-administration with efavirenz, or fluconazole had a modest effect on the pharmacokinetics of azithromycin.
Measure the oral liquid medicine with a marked measuring spoon, oral syringe, or medicine cup. Take this medicine on an empty stomach at least 1 hour before you eat, or 2 hours after you eat. Call your doctor right away if you vomit within 1 hour after you take the medicine. You must take the liquid within 12 hours after the pharmacist gives it to you. Measure your dose with a marked measuring spoon, cup, or syringe.
Mix well and drink the medicine right away. Pour another 2 ounces of water into the same glass, and drink the remaining medicine. If you are taking multiple doses, take the dose as soon as you remember. Canada residents can call a provincial poison control center. Do not share this medication with others. This medication has been prescribed for your current condition only. Do not use it later for another infection unless your doctor directs you to do so. A different medication may be necessary in that case.
If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up. Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets. Do not flush medications down the toilet or pour them into a drain unless instructed to do so.
Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.
Information last revised March Copyright c First Databank, Inc. Treating opportunistic bacterial infection in HIV with Zathrin Zathrin tablets mg contain Azithromycin, an antibiotic that is used to treat mild to moderate infections caused by certain susceptible types of bacteria in different areas of the body. People with HIV are susceptible to opportunistic infection by bacteria that lie dormant until they become activated when immunity is low. Mycobacterium avium-intracellulare complex MAC can cause infections in several organs and can lead to tuberculosis.
Zanthrin , usually in conjunction with another antibiotic, is used to prevent opportunistic infection in people with HIV. Zathrin mg tablets do not work against HIV as viruses use a different mechanism to grow and replicate. What are the side effects of Zathrin? The most common reported side effects when taking Zathrin tablets mg are gastrointestinal tract symptoms which include: Vomiting headache and dizziness may also occur as well as oral thrush white, furry, sore tongue and mouth.
These side effects are generally mild.
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© Copyright 2017 Azithromycin tablet 250mg / Azithromycin is an antibiotic used to treat many different types of infections Drug information contained herein may be time Azithromycin systemic mg..