Carcinogenesis, Mutagenesis and Impairment of Fertility No long-term studies have been performed to determine carcinogenic potential. No genetic toxicity tests have been performed. Pregnancy Category B Reproduction studies have been performed in mice and rats at doses up to 11 times the human dose and have revealed no evidence of impaired fertility or harm to the fetus due to cefadroxil monohydrate. There are, however, no adequate and well controlled studies in pregnant women.
Because animal reproduction studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed. Labor and Delivery Cefadroxil monohydrate has not been studied for use during labor and delivery. Treatment should only be given if clearly needed.
Nursing Mothers Caution should be exercised when cefadroxil monohydrate is administered to a nursing mother. No overall differences in safety were observed between the elderly patients in these studies and younger patients.
Clinical studies of cefadroxil for the treatment of pharyngitis or tonsillitis did not include sufficient numbers of patients 65 years and older to determine whether they respond differently from younger patients. Other reported clinical experience with cefadroxil has not identified differences in responses between elderly and younger patients, but greater sensitivity of some older individuals cannot be ruled out.
Because elderly patients are more likely to have decreased renal function, care should be taken in dose selection, and it may be useful to monitor renal function. Dyspepsia, nausea and vomiting have been reported rarely.
Diarrhea has also occurred. Hypersensitivity Allergies in the form of rash, urticaria, angioedema, and pruritus have been observed. These reactions usually subsided upon discontinuation of the drug. Anaphylaxis has also been reported. Other Other reactions have included hepatic dysfunction including cholestasis and elevations in serum transaminase, genital pruritus, genital moniliasis, vaginitis, moderate transient neutropenia, fever.
Agranulocytosis, thrombocytopenia, idiosyncratic hepatic failure, erythema multiforme, Stevens-Johnson syndrome, serum sickness, and arthralgia have been rarely reported. In addition to the adverse reactions listed above which have been observed in patients treated with cefadroxil, the following adverse reactions and altered laboratory tests have been reported for cephalosporin-class antibiotics: Push the plunger back into the syringe.
Keep it in a clean safe place with the medicine. Duration of treatment Treatment should be continued for at least days after the acute symptoms disappear.
In case of streptococcal infections, the minimum duration of treatment is 10 days. If you take more Cefadroxil suspension than you should If you use more Cefadroxil suspension then prescribed, immediately contact your doctor or hospital. Symptoms of overdose may include: If you forget to take Cefadroxil suspension If you forget to use this medicine, continue with your normal dosage schedule recommended by your doctor. Do not take a double dose to make up for a forgotten dose.
If you stop taking Cefadroxil suspension It is important that you take the medicine as prescribed by your doctor. Do not suddenly stop using this medication without first talking to your doctor. Otherwise, the symptoms may return. If you have any further questions on the use of this medicine, ask your doctor or pharmacist.
Possible side effects Like all medicines, this medicine can cause side effects, although not everybody gets them. If any of the following occurs, stop taking this medicine and consult your doctor immediately or go to the emergency department of the nearest hospital: Serious side effects that require emergency care: Caution is necessary in patients with renal impairment; the dosage must be adjusted according to the grade of renal impairment see section 4.
Cefadroxil should be used with caution in patients with a history of gastro-intestinal disturbances, particularly colitis. Treatment must be discontinued at once if allergic reactions occur urticaria, exanthema, pruritus, fall of blood pressure and increased heart rate, respiratory disturbances, collapse, etc. Particularly on prolonged use frequent checks on the blood count and regular hepatic and renal function tests are advisable. Superinfections with fungi e.
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